The Infinium Assay is a DNA assay developed by Illumina for whole-genome genotyping. It uses enzymes to amplify all regions of the genome simultaneously, enabling the detection of tens or hundreds of thousands or SNPs at once. When compared with assays that use PCR, this method enables high-throughput genotyping with no loss in data quality.
This is a new enzyme-utilizing assay system that does not rely on large-scale primer sets. Probes with base pair sequences specific to SNP loci and DNA samples of amplified fragments are hybridized, and a fluorescent substance is incorporated following enzyme extension reactions.